Roland Lauster Profile Page
Organisation: Technische Universität
Institute: German Rheumatism Research Center
Department: Medical Biotechnology
Address: Charitéplatz 1
10117 Berlin
Campus: Mitte
E-Mail: This e-mail address is being protected from spam bots, you need JavaScript enabled to view it
Field: Human Cell Differentiation
Track(s): Bio;Eng
CV: 2006-present Head of the Institute of Biotechnology
2005-present W3 Professor for Medical Biotechnology at the TU Berlin
2002-2005 Guest Professor for Medical Biotechnology at the TU Berlin
1996-2002 Permanent group leader position at the DRFZ
1991-1996 Post doctoral fellowship at the DRFZ, Berlin
1989-1991 Scientific member at the Basel Institute for Immunology
1987-1989 Post doctoral fellowship at the Max Planck Institute
1984-1987 PhD at the Max Planck Insitute for Molecular Genetics, Berlin
1983-1984 Diploma Thesis at the Max Planck Institute for Molecular Genetics
1980-1983 Graduate Studies in Biology at the FU Berlin
1978-1980 Undergaduate Studies in Biology at the University Bielefeld
Research Interests: differentiation and dedifferentiation of human chondrocytes

microenvironment in the human bone marrow

stem cells in the human hair follicle

mesenchymal stem cell characterization
Publications: Schaumann DH, Tuischer J, Ebell ., Manz R, Lauster R (2007) VCAM-1-positive stromal cells from human bone marrow producing cytokines for B lineage progenitors and for plasma cells: SDF-1, flt3L, and BAFF. Mol Immunol 44: 1617-1623

Rosowski M, Falb M, Tschirschmann M, Lauster R (2006) Initiation of Mesenchymal
condensation in Alginate Hollow Spheres- A useful model for understanding cartilage repair. Artificial Organs 30: 775-784

Minina E, Schneider S, Rosowski M, Lauster R and Vortkamp A (2005) Expression of Fgf and Tgfß signaling related genes during embryonic endochondral ossification. Gene Expr Patterns 6: 102-109

Bartholome B, Spies CM, Gaber T, Schuchmann S, Berki T, Kunkel D, Bienert M, Radbruch A, Burmester GR, Lauster R, Scheffold A, Buttgereit F (2004) Membrane glucocorticoid receptors (mGCR) are expressed in normal human peripheral blood mononuclear cells and up-regulated after in vitro stimulation and in patients with rheumatoid arthritis. FASEB J 18: 70-80

Nakamura M, Matzuk MM, Gerstmayer B, Bosio A, Lauster R, Miyachi Y, Werner S, Paus R (2003) Control of pelage hair follicle development and cycling by complex interactions between follistatin and activin. FASEB J 17: 497-499

Janitz M, Reiners-Schramm L, Muhlethaler-Mottet A, Rosowski M., Lauster R (2002) Analysis of the sequence polymorphism within class II transactivator gene promoters Experimental and Clinical Immunogenetics 18: 199-205

Kuon W, Holzhütter HG, Appel H, Grolms M, Kollenberger S, Traeder A, Henklein P, Weiss E, Thiel A, Lauster R, Bowness P, Radbruch A, Kloetzel PM, Sieper J (2001) Identification of HLA-B-27 restricted peptides from the Chlamydia trachomatis proteome with possible relevance to HLA-B-27 associated diseases. J Immunol 167: 4738-474

Botchkarev VA, Botchkareva NV, Nakamura M, Huber O, Funa K, Lauster R, Paus R, Gilchrest BA (2001) Noggin is required for induction of the hair follicle growth phase in postnatal skin FASEB J 15: 2205-221

Scheffold A, Assenmacher M, Reiners-Schramm L, Lauster R, Radbruch A (2000) High sensitive immunofluorescence for detection of the pro- and anti-inflammatory cytokines IFN-gamma and Il-10 on the surface of cytokine secreting cells cells. Nature Medicine 6: 107-110

Botchkarev V, Botchkareva NV, Roth W, Nakamura M, Chen LH, Herzog W, Lindner G,
McMahon J, Peters C, Lauster R, McMahon A, Paus R (1999) Noggin acts as a mesenchymally derived stimulator of hair follicle induction Nature Cell Biology 1: 158-164